OL-073 Evaluation of serum concentration of endothelium nitric oxide synthase in Helicobacter pylori positive people

Comparing Serum Levels of Autophagy-Related Gene 5 in People With and Without Helicobacter Pylori Infection

Background: Laboratory studies have shown that gastric epithelial infection cells with Helicobacter pylori (H. pylori) can increase autophagy. Disruption in this process can cause various diseases, including cancer. Objective: This study aims to compare the serum level of Autophag -Related Gene 5 (ATG5) in individuals with and without H. pylori infection. Methods: This case-control pilot stud...

Decreased Helicobacter pylori associated gastric carcinogenesis in mice lacking inducible nitric oxide synthase.

BACKGROUND AND AIMS Overproduction of nitric oxide via inducible nitric oxide synthase (iNOS) is suggested to be a significant pathogenic factor in Helicobacter pylori induced gastritis. The purpose of this study was to examine the role of iNOS in H pylori associated gastric carcinogenesis. METHODS Two types of mice were used in this study: iNOS deficient mice (iNOS-/-) and wild-type litterma...

Nitric Oxide Synthase Translation in by Attenuating Inducible Helicobacter pylori Arginase II Restricts Host Defense to

Cross-talk between inducible nitric oxide synthase and cyclooxygenase in Helicobacter-pylori-induced gastritis.

OBJECTIVES The present study examined the cross-talk between prostanoids and nitric oxide (NO) in human gastric biopsies during Helicobacter pylori infection. SUBJECTS AND METHODS A pool of 1 or 2 biopsies per patient (11 H. pylori positive and 9 H. pylori negative) were incubated in the medium with/without drugs, 1400W and NS-398, inhibitors of inducible nitric oxide synthase (iNOS) and cycl...

Association between tobacco smoke and serum nitric oxide metabolites concentration

Introduction: Cigarette smoking affects nitric oxide production. The aim of this study was to determine associations between tobacco smoke and serum nitric oxide metabolites (NOx) concentration. Methods: Serum NOx concentration was measured by the Griess method in 230 nonsmokers, 238 active, 196 passive and 29 waterpipe smokers. Subjects were selected from participants of Tehran Lipid and Gl...